Sunil lowres copy

ESR 13

Primary Supervisor: Prof Leonor Cancela

Co-supervisor: Prof Paulo Gavaia

EDUCATION

Masters in Pharmaceutical Science and Technology (specialising in Molecular Metabolism) from Daegu Catholic University, South Korea.  Bachelor of Science in Medical Laboratory Technology (Medical Laboratory Science) from Pokhara University, Nepal.

SCIENTIFIC WORK EXPERIENCE

Sunil initially specialised as Medical Laboratory Technologist in Nepal with a B.Sc. in Medical Laboratory Technology from Pokhara University with a research project on Inter co-relation among markers of T cell (CD3, CD4) and CD4 with Total lymphocyte Count in HIV patient published in a scientific journal.  This provided a solid foundation covering clinical specialization on Pathology including its branch as clinical biochemistry, haematology, clinical laboratory research, molecular cell biology, microbiology, immunology, histopathology, biostatistics and research methodology.  With over 4 years of experience in clinical laboratories at the Department of Pathology, he was able to utilise his analytical and quantitative reasoning taught in the classroom.  Along with routine diagnostic experience within a pathology laboratory setting I developed numerous hypotheses, some of which generated publications. 

Sunil completed a Masters in Pharmaceutical Science and Technology specialising in Molecular Metabolism from Daegu Catholic University, South Korea, with a research project in a laboratory focused on glucose metabolism.  He developed an interest in bone biology, so he chose to investigate the role of Pyruvate dehydrogenase kinase (PDK) on bone-forming osteoblasts.  He also noted that Suramin, a century old drug whose mechanism of action was still unknown, had significantly increased blood glucose in patient while in therapy.  From here, Sunil hypothesised that Suramin can also interfere in glucose mechanism.  Using in vitro models he was able to explain the mechanism of action of Suramin and the role of PDKs in osteoblast differentiation. 

Sunil has a strong research foundation with many relevant practical skills including cell culture, cancer cell handling and culture, stem cell differentiation, ELISA technique, Osteoblast  Cell Culture and differentiation, Western Blotting, In-VIVO (zebra fish, mouse), cardiac perfusion, Brain isolation and clearing, Primary cell isolation and culture, B-cell and T-cell isolation and culture, Primary bone cell isolation and culture, UV Spectrophotometry, Liquid chromatography, RT-PCR, Flow cytometry, Cloning, Enzyme assay HPLC, Sigma Plot, Sigma Stat, PRISM, SPSS. Viral load assay, Dried blood spot assay, Phlebotomy and almost all Pathology based techniques including I clinical Biochemistry, Microbiology, Heamatology, Histo and Cytopathology and Blood bank.

OTHER HIGHLIGHTS

Sunil is trained in bone marrow transplant from Christian Medical College, Vellore, India.  He is fluent in English, Hindi, Urdu and Japanese.  Nepali is his mother tongue and he has some knowledge of German.  Sunil has a keen interest in photography.  Last but not least, he is vegetarian.

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